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The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology

Edited by Ford F. Synthesizing current information about sensory-motor plasticity, Neural Plasticity in Adult Somatic Sensory-Motor Systems provides an up-to-date description of the dynamic processes that occur in somatic sensory-motor cortical circuits or somatic sensory pathways to the cortex due to experience,…. Edited by Dennis A. Focusing on how increased understanding of brain function affects clinical neuroscience, this incisive text explores the interface between neuroscience and clinical neuroscience advances by examining the hypotheses that drive this evolution.

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The phenomenon has been studied in humans and animals, yet until now, there has been no publication to successfully…. Recent years have seen an explosion of activity in the field of biomedical imaging in an attempt to understand the behavior of the brain in healthy and disease states. With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting….

Edited by Barry D. The field of drug addiction and substance abuse, which was initially confined to behavioral studies, has broadened dramatically. It now includes a vast array of cellular and molecular approaches as well as sophisticated electrophysiological and neurochemical methodologies that bridge the gap…. Edited by Asif A. Like speech, the species-specific vocalizations or calls of non-human primates mediate social interactions, convey important emotional information, and in some cases refer to objects and events in the caller's environment.

These functional similarities suggest that the selective pressures which…. Edited by Yuan Liu , David M. Neuroscience research in alcohol-related disorders has made remarkable progress in the last two decades. The advances are due, in great part, to the large array of powerful biomedical, bioengineering, and computational biological techniques that are now employed. To date, there has not been a…. Edited by Elena V. A quantum leap in technology took place a few years ago with the introduction of cDNA arrays that have been developed in response to the need for simultaneous analysis of the patterns of expression of thousands of genes.

Edited by Rick C. Approximately half a million Americans suffer brain ischemic episodes every year.

Molecular Methods in Ionotropic Receptor Biology, 1st Edition

These brain strokes are the third leading cause of death in the United States and the number-one cause of permanent disability. Over the past decade, we have made extensive attempts to understand the biological…. Edited by Sidney A. Simon , Miguel A. Written by world experts in the field of neuronal chemoreception, Methods in Chemosensory Research describes new molecular, electrophysiological, genetic, behavioral, psychophysical, and imaging techniques that have recently been adapted to investigate the basic neuronal mechanisms underlying….

Edited by Hemin R. Chin , Steven O. The past few years have witnessed extraordinary advances in molecular genetic techniques and the accumulation of structural genomics information and resources in both human and model organisms.

With the development of new technologies and the availability of resources like the sequence of…. Edited by Edward D. Nicotine research has been conducted for the better part of a century, but with the discovery of the relationship of nicotinic systems to Alzheimer's disease, the differentiation of nicotinic receptor subtypes, and the development of novel nicotinic ligands, the field of nicotine research has….


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Edited by Timothy C. Traumatic injuries of the spinal cord continue to be the most common cause of permanent paralysis in young adults in the United States. New information has emerged on the response of spinal neurons to injury of either the spinal cord or peripheral nerves demonstrating that dendrites of injured…. Edited by Erik De Schutter. Designed primarily as an introduction to realistic modeling methods, Computational Neuroscience: Realistic Modeling for Experimentalists focuses on methodological approaches, selecting appropriate methods, and identifying potential pitfalls.

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The dynamic synapse molecular methods in ionotropic receptor biology

Edited by Yusuf A. Hannun , Rose-Mary Boustany. The rapid growth of the study of apoptosis-mechanism-driven, regulated cell death-has created an urgent need for reliable documentation of the different approaches to and methods of studying the various aspects of the field. Apoptosis in Neurobiology is an important resource for researchers in this…. Frontiers in Neuroscience Series Editor:. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse… Paperback — CRC Press Frontiers in Neuroscience.

Torres , Caroline Whyatt Autism: The Movement Sensing Perspective is the result of a collaborative effort by parents, therapists, clinicians, and researchers from all disciplines in science including physics, engineering, and applied mathematics. Koob Understanding the phenomenon of long-lasting vulnerability to addiction is essential to developing successful treatments. Neurobiology of TRP Channels 1st Edition Edited by Tamara Luti Rosenbaum Emir During the last two decades, there has been an explosion of research pertaining to the molecular mechanisms that allow for organisms to detect different stimuli that is an essential feature for their survival.

Written by world-renowned leaders in the field, the book delineates newly developed techniques, methods, and conceptual advances used for studying neurotransmitter receptors and other synaptic proteins. A broad array of molecular, biochemical, imaging, and electrophysiological approaches for studying the biology of synapses are described.

Specific topics include the use of proteomics to study synaptic protein complexes, the development of phosphorylation state-specific antibodies, post-genomic tools applied to the study of synapses, and RNA interference in neurons.

The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology

In addition, several chapters focus on methods for gene and protein delivery into neuronal tissue. The use of biochemical, electrophysiological, and optical tagging techniques to study the movement and membrane trafficking of neurotransmitter receptors in the membranes of live nerve cells are also discussed. To complement these approaches, the application of state-of-the-art approaches for achieving long-term alterations in the genetic complement of neurons in vivo using viral vectors or homologous recombinations of ES cells is also described.

This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use.